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Molecular evidence for the bi-clonal origin of neuroendocrine tumor derived metastases

BACKGROUND: Reports on common mutations in neuroendocrine tumors (NET) are rare and clonality of NET metastases has not been investigated in this tumor entity yet. We selected one NET and the corresponding lymph node and liver metastases as well as the derivative cell lines to screen for somatic mut...

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Detalles Bibliográficos
Autores principales: Rinner, Beate, Gallè, Birgit, Trajanoski, Slave, Fischer, Carina, Hatz, Martina, Maierhofer, Theresa, Michelitsch, Gabriele, Moinfar, Farid, Stelzer, Ingeborg, Pfragner, Roswitha, Guelly, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500212/
https://www.ncbi.nlm.nih.gov/pubmed/23127113
http://dx.doi.org/10.1186/1471-2164-13-594