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Molecular heterogeneity in malignant peripheral nerve sheath tumors associated with neurofibromatosis type 1

Neurofibromatosis type-1 (NF1), resulting from NF1 gene loss of function, is characterized by an increased risk of developing benign and malignant peripheral nerve sheath tumors (MPNSTs). Whereas the cellular heterogeneity of NF1-associated tumors has been well studied, the molecular heterogeneity o...

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Detalles Bibliográficos
Autores principales: Thomas, Laura, Mautner, Victor-Felix, Cooper, David N, Upadhyaya, Meena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500234/
https://www.ncbi.nlm.nih.gov/pubmed/23244685
http://dx.doi.org/10.1186/1479-7364-6-18