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Comparative exome sequencing of metastatic lesions provides insights into the mutational progression of melanoma

BACKGROUND: Metastasis is characterized by spreading of neoplastic cells to an organ other than where they originated and is the predominant cause of death among cancer patients. This holds true for melanoma, whose incidence is increasing more rapidly than any other cancer and once disseminated has...

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Detalles Bibliográficos
Autores principales: Gartner, Jared J, Davis, Sean, Wei, Xiaomu, Lin, Jimmy C, Trivedi, Niraj S, Teer, Jamie K, Meltzer, Paul S, Rosenberg, Steven A, Samuels, Yardena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500261/
https://www.ncbi.nlm.nih.gov/pubmed/23006843
http://dx.doi.org/10.1186/1471-2164-13-505