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New Alternately Colored FRET Sensors for Simultaneous Monitoring of Zn(2+) in Multiple Cellular Locations

Genetically encoded sensors based on fluorescence resonance energy transfer (FRET) are powerful tools for reporting on ions, molecules and biochemical reactions in living cells. Here we describe the development of new sensors for Zn(2+)based on alternate FRET-pairs that do not involve the traditiona...

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Detalles Bibliográficos
Autores principales: Miranda, Jose G., Weaver, Amanda L., Qin, Yan, Park, J. Genevieve, Stoddard, Caitlin I., Lin, Michael Z., Palmer, Amy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500285/
https://www.ncbi.nlm.nih.gov/pubmed/23173058
http://dx.doi.org/10.1371/journal.pone.0049371