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Xanthohumol Prevents Atherosclerosis by Reducing Arterial Cholesterol Content via CETP and Apolipoprotein E in CETP-Transgenic Mice

BACKGROUND: Xanthohumol is expected to be a potent anti-atherosclerotic agent due to its inhibition of cholesteryl ester transfer protein (CETP). In this study, we hypothesized that xanthohumol prevents atherosclerosis in vivo and used CETP-transgenic mice (CETP-Tg mice) to evaluate xanthohumol as a...

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Detalles Bibliográficos
Autores principales: Hirata, Hiroshi, Yimin, Segawa, Shuichi, Ozaki, Moeko, Kobayashi, Naoyuki, Shigyo, Tatsuro, Chiba, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500296/
https://www.ncbi.nlm.nih.gov/pubmed/23166663
http://dx.doi.org/10.1371/journal.pone.0049415