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Xanthohumol Prevents Atherosclerosis by Reducing Arterial Cholesterol Content via CETP and Apolipoprotein E in CETP-Transgenic Mice
BACKGROUND: Xanthohumol is expected to be a potent anti-atherosclerotic agent due to its inhibition of cholesteryl ester transfer protein (CETP). In this study, we hypothesized that xanthohumol prevents atherosclerosis in vivo and used CETP-transgenic mice (CETP-Tg mice) to evaluate xanthohumol as a...
Autores principales: | Hirata, Hiroshi, Yimin, Segawa, Shuichi, Ozaki, Moeko, Kobayashi, Naoyuki, Shigyo, Tatsuro, Chiba, Hitoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500296/ https://www.ncbi.nlm.nih.gov/pubmed/23166663 http://dx.doi.org/10.1371/journal.pone.0049415 |
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