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The rs1024611 Regulatory Region Polymorphism Is Associated with CCL2 Allelic Expression Imbalance

CC chemokine ligand 2 (CCL2) is the most potent monocyte chemoattractant and inter-individual differences in its expression level have been associated with genetic variants mapping to the cis-regulatory regions of the gene. An A to G polymorphism in the CCL2 enhancer region at position –2578 (rs1024...

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Detalles Bibliográficos
Autores principales: Pham, Minh-Hieu T., Bonello, Gregory B., Castiblanco, John, Le, Tuan, Sigala, Jose, He, Weijing, Mummidi, Srinivas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500309/
https://www.ncbi.nlm.nih.gov/pubmed/23166687
http://dx.doi.org/10.1371/journal.pone.0049498