A Novel Role of Human Holliday Junction Resolvase GEN1 in the Maintenance of Centrosome Integrity

The maintenance of genomic stability requires accurate genome replication, repair of DNA damage, and the precise segregation of chromosomes in mitosis. GEN1 possesses Holliday junction resolvase activity in vitro and presumably functions in homology driven repair of DNA double strand breaks. However...

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Detalles Bibliográficos
Autores principales: Gao, Min, Rendtlew Danielsen, Jannie, Wei, Lei-Zhen, Zhou, Dong-Ping, Xu, Qian, Li, Miao-Miao, Wang, Zhao-Qi, Tong, Wei-Min, Yang, Yun-Gui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500319/
https://www.ncbi.nlm.nih.gov/pubmed/23166748
http://dx.doi.org/10.1371/journal.pone.0049687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500319/
https://www.ncbi.nlm.nih.gov/pubmed/23166748
http://dx.doi.org/10.1371/journal.pone.0049687

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