Sulforaphane Inhibits Prostaglandin E2 Synthesis by Suppressing Microsomal Prostaglandin E Synthase 1

Sulforaphane (SFN) is a dietary cancer preventive with incompletely characterized mechanism(s) of cancer prevention. Since prostaglandin E2 (PGE2) promotes cancer progression, we hypothesized that SFN may block PGE2 synthesis in cancer cells. We found that SFN indeed blocked PGE2 production in human...

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Detalles Bibliográficos
Autores principales: Zhou, Jiping, Joplin, Denise G., Cross, Janet V., Templeton, Dennis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500324/
https://www.ncbi.nlm.nih.gov/pubmed/23166763
http://dx.doi.org/10.1371/journal.pone.0049744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500324/
https://www.ncbi.nlm.nih.gov/pubmed/23166763
http://dx.doi.org/10.1371/journal.pone.0049744

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