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A Quantitative Proteomic Profile of the Nrf2-Mediated Antioxidant Response of Macrophages to Oxidized LDL Determined by Multiplexed Selected Reaction Monitoring

The loading of macrophages with oxidized low density lipoprotein (LDL) is a key part of the initiation and progression of atherosclerosis. Oxidized LDL contains a wide ranging set of toxic species, yet the molecular events that allow macrophages to withstand loading with these toxic species are not...

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Detalles Bibliográficos
Autores principales: Kinter, Caroline S., Lundie, Jillian M., Patel, Halee, Rindler, Paul M., Szweda, Luke I., Kinter, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500347/
https://www.ncbi.nlm.nih.gov/pubmed/23166812
http://dx.doi.org/10.1371/journal.pone.0050016