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Siglec-6 is expressed in gestational trophoblastic disease and affects proliferation, apoptosis and invasion

Sialic acid immunoglobulin-like lectin (Siglec)-6 is a transmembrane receptor that binds leptin. Leptin is an obesity-associated peptide hormone overexpressed in gestational trophoblastic disease (GTD). GTD encompasses several placental abnormalities that range from benign to malignant. Among GTD, m...

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Detalles Bibliográficos
Autores principales: Rumer, Kristen K, Post, Miriam D, Larivee, Rhea S, Zink, Martina, Uyenishi, Jill, Kramer, Anita, Teoh, Deanna, Bogart, Kevin, Winn, Virginia D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Endocrinology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500471/
https://www.ncbi.nlm.nih.gov/pubmed/23089140
http://dx.doi.org/10.1530/ERC-11-0379