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Application of circular consensus sequencing and network analysis to characterize the bovine IgG repertoire

BACKGROUND: Vertebrate immune systems generate diverse repertoires of antibodies capable of mediating response to a variety of antigens. Next generation sequencing methods provide unique approaches to a number of immuno-based research areas including antibody discovery and engineering, disease surve...

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Detalles Bibliográficos
Autores principales: Larsen, Peter A, Smith, Timothy P L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500647/
https://www.ncbi.nlm.nih.gov/pubmed/22978666
http://dx.doi.org/10.1186/1471-2172-13-52