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Application of circular consensus sequencing and network analysis to characterize the bovine IgG repertoire
BACKGROUND: Vertebrate immune systems generate diverse repertoires of antibodies capable of mediating response to a variety of antigens. Next generation sequencing methods provide unique approaches to a number of immuno-based research areas including antibody discovery and engineering, disease surve...
Autores principales: | Larsen, Peter A, Smith, Timothy P L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500647/ https://www.ncbi.nlm.nih.gov/pubmed/22978666 http://dx.doi.org/10.1186/1471-2172-13-52 |
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