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Mechanisms of the antinociceptive action of (−) Epicatechin obtained from the hydroalcoholic fraction of Combretum leprosum Mart & Eic in rodents

BACKGROUND: The mechanisms of the antinociceptive activity of (−) epicatechin (EPI), a compound isolated from the hydroalcoholic fraction of Combreum leprosum Mart & Eicher. METHODS: were assessed in the model of chemical nociception induced by glutamate (20 μmol/paw). To evaluate the mechanisms...

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Detalles Bibliográficos
Autores principales: Lopes, Luciano da Silva, Marques, Rosemarie Brandin, Fernandes, Heliana Barros, Pereira, Sergio da Silva, Ayres, Mariane CC, Chaves, Mariana Helena, Almeida, Fernanda RC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500648/
https://www.ncbi.nlm.nih.gov/pubmed/22830928
http://dx.doi.org/10.1186/1423-0127-19-68