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BCL10GFP fusion protein as a substrate for analysis of determinants required for Mucosa-Associated Lymphoid Tissue 1 (MALT1)-mediated cleavage

BACKGROUND: MALT1 belongs to a family of paracaspase and modulates NF-κB signaling pathways through its scaffolding function and proteolytic activity. MALT1 cleaves protein substrates after a positively charged Arginine residue. BCL10, a 233 amino acids polypeptide, is identified as one of the MALT1...

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Detalles Bibliográficos
Autores principales: Jou, Shin-Yi, Chang, Chien-Chih, Wu, Chun-Hsien, Chen, Mei-Ru, Tsai, Ching-Hwa, Chuang, Wen-Hui, Chen, Yun-Hui, Cheng, Ann-Lii, Doong, Shin-Lian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500650/
https://www.ncbi.nlm.nih.gov/pubmed/23035874
http://dx.doi.org/10.1186/1423-0127-19-85