Endothelial cell dysfunction and cytoskeletal changes associated with repression of p16(INK4a) during immortalization

The immortalization process is a fundamental step in the development of most (if not all) human cancers, including the aggressive endothelial cell (EC)-derived malignancy angiosarcoma. Inactivation of the tumor suppressor p16(INK4a) and the development of multiple chromosomal abnormalities are featu...

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Detalles Bibliográficos
Autores principales: Kan, C-Y, Wen, V W, Pasquier, E, Jankowski, K, Chang, M, Richards, L A, Kavallaris, M, MacKenzie, K L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500701/
https://www.ncbi.nlm.nih.gov/pubmed/22310292
http://dx.doi.org/10.1038/onc.2011.645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500701/
https://www.ncbi.nlm.nih.gov/pubmed/22310292
http://dx.doi.org/10.1038/onc.2011.645

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