Structural and Molecular Conservation of Glucagon-Like Peptide-1 and Its Receptor Confers Selective Ligand-Receptor Interaction

Glucagon-like peptide-1 (GLP-1) is a major player in the regulation of glucose homeostasis. It acts on pancreatic beta cells to stimulate insulin secretion and on the brain to inhibit appetite. Thus, it may be a promising therapeutic agent for the treatment of type 2 diabetes mellitus and obesity. D...

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Detalles Bibliográficos
Autores principales: Moon, Mi Jin, Park, Sumi, Kim, Dong-Kyu, Cho, Eun Bee, Hwang, Jong-Ik, Vaudry, Hubert, Seong, Jae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500760/
https://www.ncbi.nlm.nih.gov/pubmed/23181056
http://dx.doi.org/10.3389/fendo.2012.00141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500760/
https://www.ncbi.nlm.nih.gov/pubmed/23181056
http://dx.doi.org/10.3389/fendo.2012.00141

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