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Structural and Molecular Conservation of Glucagon-Like Peptide-1 and Its Receptor Confers Selective Ligand-Receptor Interaction
Glucagon-like peptide-1 (GLP-1) is a major player in the regulation of glucose homeostasis. It acts on pancreatic beta cells to stimulate insulin secretion and on the brain to inhibit appetite. Thus, it may be a promising therapeutic agent for the treatment of type 2 diabetes mellitus and obesity. D...
Autores principales: | Moon, Mi Jin, Park, Sumi, Kim, Dong-Kyu, Cho, Eun Bee, Hwang, Jong-Ik, Vaudry, Hubert, Seong, Jae Young |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500760/ https://www.ncbi.nlm.nih.gov/pubmed/23181056 http://dx.doi.org/10.3389/fendo.2012.00141 |
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