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Modeling the Mechanism of GR/c-Jun/Erg Crosstalk in Apoptosis of Acute Lymphoblastic Leukemia

Acute lymphoblastic leukemia (ALL) is one of the most common forms of malignancy that occurs in lymphoid progenitor cells, particularly in children. Synthetic steroid hormones glucocorticoids (GCs) are widely used as part of the ALL treatment regimens due to their apoptotic function, but their use a...

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Detalles Bibliográficos
Autores principales: Chen, Daphne Wei-Chen, Krstic-Demonacos, Marija, Schwartz, Jean-Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500877/
https://www.ncbi.nlm.nih.gov/pubmed/23181019
http://dx.doi.org/10.3389/fphys.2012.00410