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Maintenance of a Vertebrate Constitutive Heterochromatin Domain by a Dicer-dependent Mechanism

The 16 kb heterochromatin domain between the chicken β-globin locus and the folate receptor gene is used here to study the roles of RNA dependent mechanisms and histone modifications in maintenance of a constitutively heterochromatic structure. Inhibition of HDAC activity is shown to both increase i...

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Detalles Bibliográficos
Autores principales: Giles, Keith E., Ghirlando, Rodolfo, Felsenfeld, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500915/
https://www.ncbi.nlm.nih.gov/pubmed/20010811
http://dx.doi.org/10.1038/ncb2010