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Maintenance of a Vertebrate Constitutive Heterochromatin Domain by a Dicer-dependent Mechanism
The 16 kb heterochromatin domain between the chicken β-globin locus and the folate receptor gene is used here to study the roles of RNA dependent mechanisms and histone modifications in maintenance of a constitutively heterochromatic structure. Inhibition of HDAC activity is shown to both increase i...
Autores principales: | Giles, Keith E., Ghirlando, Rodolfo, Felsenfeld, Gary |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500915/ https://www.ncbi.nlm.nih.gov/pubmed/20010811 http://dx.doi.org/10.1038/ncb2010 |
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