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Neuroplastic alteration of TTX-resistant sodium channel with visceral pain and morphine-induced hyperalgesia

The discovery of the tetrodotoxin-resistant (TTX-R) Na(+) channel in nociceptive neurons has provided a special target for analgesic intervention. In a previous study we found that both morphine tolerance and persistent visceral inflammation resulted in visceral hyperalgesia. It has also been sugges...

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Detalles Bibliográficos
Autores principales: Chen, Jinghong, Gong, Ze-hui, Yan, Hao, Qiao, Zhijun, Qin, Bo-yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500918/
https://www.ncbi.nlm.nih.gov/pubmed/23166448
http://dx.doi.org/10.2147/JPR.S27751