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Neuroplastic alteration of TTX-resistant sodium channel with visceral pain and morphine-induced hyperalgesia
The discovery of the tetrodotoxin-resistant (TTX-R) Na(+) channel in nociceptive neurons has provided a special target for analgesic intervention. In a previous study we found that both morphine tolerance and persistent visceral inflammation resulted in visceral hyperalgesia. It has also been sugges...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500918/ https://www.ncbi.nlm.nih.gov/pubmed/23166448 http://dx.doi.org/10.2147/JPR.S27751 |