Repeat-dose steady-state pharmacokinetic evaluation of once-daily hydromorphone extended-release (OROS(®) hydromorphone ER) in patients with chronic pain

OBJECTIVE: To characterize the steady-state pharmacokinetic profile of hydromorphone extended-release (ER) in patients with chronic pain taking concomitant medications. METHODS: This open-label repeat-dose study enrolled 22 patients (mean age, 51.4 years; 81.8% female). All patients were receiving a...

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Detalles Bibliográficos
Autores principales: Vandenbossche, Joris, Richarz, Ute, Richards, Henry M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500920/
https://www.ncbi.nlm.nih.gov/pubmed/23166450
http://dx.doi.org/10.2147/JPR.S33807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500920/
https://www.ncbi.nlm.nih.gov/pubmed/23166450
http://dx.doi.org/10.2147/JPR.S33807

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