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A large animal neuropathic pain model in sheep: a strategy for improving the predictability of preclinical models for therapeutic development
BACKGROUND: Evaluation of analgesics in large animals is a necessary step in the development of better pain medications or gene therapy prior to clinical trials. However, chronic neuropathic pain models in large animals are limited. To address this deficiency, we developed a neuropathic pain model i...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500921/ https://www.ncbi.nlm.nih.gov/pubmed/23166445 http://dx.doi.org/10.2147/JPR.S34977 |