A large animal neuropathic pain model in sheep: a strategy for improving the predictability of preclinical models for therapeutic development

BACKGROUND: Evaluation of analgesics in large animals is a necessary step in the development of better pain medications or gene therapy prior to clinical trials. However, chronic neuropathic pain models in large animals are limited. To address this deficiency, we developed a neuropathic pain model i...

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Detalles Bibliográficos
Autores principales: Wilkes, Denise, Li, Guangwen, Angeles, Carmina F, Patterson, Joel T, Huang, Li-Yen Mae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500921/
https://www.ncbi.nlm.nih.gov/pubmed/23166445
http://dx.doi.org/10.2147/JPR.S34977

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