Skin permeability and pharmacokinetics of diclofenac epolamine administered by dermal patch in Yorkshire-Landrace pigs

PURPOSE: This study compared the pharmacokinetic profile, and systemic and local absorption of diclofenac, following dermal patch application and oral administration in Yorkshire-Landrace pigs. PATIENTS AND METHODS: Twelve anesthetized, female, Yorkshire-Landrace pigs were randomized to receive eith...

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Detalles Bibliográficos
Autores principales: Tse, Susanna, Powell, Kendall D, MacLennan, Stephen J, Moorman, Allan R, Paterson, Craig, Bell, Rosonald R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500922/
https://www.ncbi.nlm.nih.gov/pubmed/23166444
http://dx.doi.org/10.2147/JPR.S35450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500922/
https://www.ncbi.nlm.nih.gov/pubmed/23166444
http://dx.doi.org/10.2147/JPR.S35450

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