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Skin permeability and pharmacokinetics of diclofenac epolamine administered by dermal patch in Yorkshire-Landrace pigs

PURPOSE: This study compared the pharmacokinetic profile, and systemic and local absorption of diclofenac, following dermal patch application and oral administration in Yorkshire-Landrace pigs. PATIENTS AND METHODS: Twelve anesthetized, female, Yorkshire-Landrace pigs were randomized to receive eith...

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Detalles Bibliográficos
Autores principales:	Tse, Susanna, Powell, Kendall D, MacLennan, Stephen J, Moorman, Allan R, Paterson, Craig, Bell, Rosonald R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2012
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500922/ https://www.ncbi.nlm.nih.gov/pubmed/23166444 http://dx.doi.org/10.2147/JPR.S35450

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