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Crucial involvement of actin filaments in celecoxib and morphine analgesia in a model of inflammatory pain

BACKGROUND: Celecoxib exerted analgesic effects (hypoalgesia) reversed by opioid receptor antagonists in a model of inflammatory pain. To analyze this celecoxib-induced hypoalgesia further, we assessed the effects of several disruptors of cytoskeletal components in our model of inflammation. METHODS...

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Detalles Bibliográficos
Autores principales: Paiva-Lima, Patrícia, Rezende, Rafael M, Leite, Rômulo, Duarte, Igor DG, Bakhle, YS, Francischi, Janetti N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500925/
https://www.ncbi.nlm.nih.gov/pubmed/23166451
http://dx.doi.org/10.2147/JPR.S36870