Role of Glyoxalase 1 (Glo1) and methylglyoxal (MG) in behavior: recent advances and mechanistic insights

Glyoxalase 1 (GLO1) is a ubiquitous cellular enzyme that participates in the detoxification of methylglyoxal (MG), a cytotoxic byproduct of glycolysis that induces protein modification (advanced glycation end-products, AGEs), oxidative stress, and apoptosis. The concentration of MG is elevated under...

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Detalles Bibliográficos
Autores principales: Distler, Margaret G., Palmer, Abraham A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500958/
https://www.ncbi.nlm.nih.gov/pubmed/23181072
http://dx.doi.org/10.3389/fgene.2012.00250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500958/
https://www.ncbi.nlm.nih.gov/pubmed/23181072
http://dx.doi.org/10.3389/fgene.2012.00250

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