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Chromatin modifying enzymes as modulators of reprogramming

Generation of induced pluripotent stem cells (iPSCs) by somatic cell reprogramming involves global epigenetic remodeling(1). While several proteins are known to regulate chromatin marks associated with the distinct epigenetic states of cells before and after reprogramming(2,3), the role of specific...

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Detalles Bibliográficos
Autores principales: Onder, Tamer T., Kara, Nergis, Cherry, Anne, Sinha, Amit U., Zhu, Nan, Bernt, Kathrin M., Cahan, Patrick, Mancarci, Ogan. B., Unternaehrer, Juli, Gupta, Piyush B., Lander, Eric S., Armstrong, Scott A., Daley, George Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501145/
https://www.ncbi.nlm.nih.gov/pubmed/22388813
http://dx.doi.org/10.1038/nature10953