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Total Body Irradiation With Lung Dose-Reduction Does Not Improve Hematopoietic Cell Homing to Bone Marrow During Allogeneic Transplantation

PURPOSE: To determine the effects of total body irradiation (TBI) dose, fractionation, and lung shielding on hematopoietic stem cell homing to the bone marrow. MATERIAL AND METHODS: Bone marrow (BM) cells were extracted from tibiae and femurs of B6-GFP mice and were transplanted into B6 mice. Recipi...

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Detalles Bibliográficos
Autores principales: Singh, Anurag K., Chen, Jichun, Calado, Rodrigo, Sowers, Anastasia, Mitchell, James B., Barrett, A. John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501194/
https://www.ncbi.nlm.nih.gov/pubmed/19525987
http://dx.doi.org/10.1038/bmt.2009.121