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No evidence for genetic association with the let-7 microRNA-binding site or other common KRAS variants in risk of endometriosis

STUDY QUESTION: Is there a contribution of the minor allele at the KRAS single nucleotide polymorphism (SNP) rs61764370 in the let-7 microRNA-binding site to endometriosis risk? SUMMARY ANSWER: We found no evidence for association between endometriosis risk and rs61764370 or any other SNPs in KRAS....

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Detalles Bibliográficos
Autores principales: Luong, Hien T.T., Nyholt, Dale R., Painter, Jodie N., Chapman, Brett, Kennedy, Stephen, Treloar, Susan A., Zondervan, Krina T., Montgomery, Grant W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501245/
https://www.ncbi.nlm.nih.gov/pubmed/23010532
http://dx.doi.org/10.1093/humrep/des329