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ProNGF, a cytokine induced after myocardial infarction in humans, targets pericytes to promote microvascular damage and activation

Treatment of acute cardiac ischemia focuses on reestablishment of blood flow in coronary arteries. However, impaired microvascular perfusion damages peri-infarct tissue, despite arterial patency. Identification of cytokines that induce microvascular dysfunction would provide new targets to limit mic...

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Detalles Bibliográficos
Autores principales: Siao, Chia-Jen, Lorentz, Christina U., Kermani, Pouneh, Marinic, Tina, Carter, John, McGrath, Kelly, Padow, Victoria A., Mark, Willie, Falcone, Domenick J., Cohen-Gould, Leona, Parrish, Diana C., Habecker, Beth A., Nykjaer, Anders, Ellenson, Lora H., Tessarollo, Lino, Hempstead, Barbara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501352/
https://www.ncbi.nlm.nih.gov/pubmed/23091165
http://dx.doi.org/10.1084/jem.20111749