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ProNGF, a cytokine induced after myocardial infarction in humans, targets pericytes to promote microvascular damage and activation
Treatment of acute cardiac ischemia focuses on reestablishment of blood flow in coronary arteries. However, impaired microvascular perfusion damages peri-infarct tissue, despite arterial patency. Identification of cytokines that induce microvascular dysfunction would provide new targets to limit mic...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501352/ https://www.ncbi.nlm.nih.gov/pubmed/23091165 http://dx.doi.org/10.1084/jem.20111749 |