Congenital B cell lymphocytosis explained by novel germline CARD11 mutations

Nuclear factor-κB (NF-κB) controls genes involved in normal lymphocyte functions, but constitutive NF-κB activation is often associated with B cell malignancy. Using high-throughput whole transcriptome sequencing, we investigated a unique family with hereditary polyclonal B cell lymphocytosis. We fo...

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Detalles Bibliográficos
Autores principales: Snow, Andrew L., Xiao, Wenming, Stinson, Jeffrey R., Lu, Wei, Chaigne-Delalande, Benjamin, Zheng, Lixin, Pittaluga, Stefania, Matthews, Helen F., Schmitz, Roland, Jhavar, Sameer, Kuchen, Stefan, Kardava, Lela, Wang, Wei, Lamborn, Ian T., Jing, Huie, Raffeld, Mark, Moir, Susan, Fleisher, Thomas A., Staudt, Louis M., Su, Helen C., Lenardo, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501355/
https://www.ncbi.nlm.nih.gov/pubmed/23129749
http://dx.doi.org/10.1084/jem.20120831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501355/
https://www.ncbi.nlm.nih.gov/pubmed/23129749
http://dx.doi.org/10.1084/jem.20120831

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