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Cellular origin and pathophysiology of chronic lymphocytic leukemia

The cellular origin of chronic lymphocytic leukemia (CLL) is still debated, although this information is critical to understanding its pathogenesis. Transcriptome analyses of CLL and the main normal B cell subsets from human blood and spleen revealed that immunoglobulin variable region (IgV) gene un...

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Detalles Bibliográficos
Autores principales: Seifert, Marc, Sellmann, Ludger, Bloehdorn, Johannes, Wein, Frederik, Stilgenbauer, Stephan, Dürig, Jan, Küppers, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501361/
https://www.ncbi.nlm.nih.gov/pubmed/23091163
http://dx.doi.org/10.1084/jem.20120833