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γ-H2AX expression detected by immunohistochemistry correlates with prognosis in early operable non-small cell lung cancer

BACKGROUND: Phosphorylation of the H2AX histone is an early indicator of DNA double-strand breaks and of the resulting DNA damage response. In the present study, we assessed the expression and prognostic significance of γ-H2AX in a cohort of 96 patients with operable non-small cell lung carcinoma. M...

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Detalles Bibliográficos
Autores principales: Matthaios, Dimitrios, Foukas, Periklis G, Kefala, Maria, Hountis, Panagiotis, Trypsianis, Grigorios, Panayiotides, Ioannis G, Chatzaki, Ekaterini, Pantelidaki, Ekaterini, Bouros, Demosthenes, Karakitsos, Petros, Kakolyris, Stylianos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501397/
https://www.ncbi.nlm.nih.gov/pubmed/23180966
http://dx.doi.org/10.2147/OTT.S36995