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γ-H2AX expression detected by immunohistochemistry correlates with prognosis in early operable non-small cell lung cancer
BACKGROUND: Phosphorylation of the H2AX histone is an early indicator of DNA double-strand breaks and of the resulting DNA damage response. In the present study, we assessed the expression and prognostic significance of γ-H2AX in a cohort of 96 patients with operable non-small cell lung carcinoma. M...
Autores principales: | Matthaios, Dimitrios, Foukas, Periklis G, Kefala, Maria, Hountis, Panagiotis, Trypsianis, Grigorios, Panayiotides, Ioannis G, Chatzaki, Ekaterini, Pantelidaki, Ekaterini, Bouros, Demosthenes, Karakitsos, Petros, Kakolyris, Stylianos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501397/ https://www.ncbi.nlm.nih.gov/pubmed/23180966 http://dx.doi.org/10.2147/OTT.S36995 |
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