VLPs Displaying a Single L2 Epitope Induce Broadly Cross-Neutralizing Antibodies against Human Papillomavirus

BACKGROUND: Virus-like Particles (VLPs) display can be used to increase the immunogenicity of heterologous antigens. Here, we report the use of a bacteriophage MS2-based VLP display platform to develop a monovalent vaccine targeting a broadly neutralizing epitope in the minor capsid protein human pa...

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Detalles Bibliográficos
Autores principales: Tumban, Ebenezer, Peabody, Julianne, Tyler, Mitchell, Peabody, David S., Chackerian, Bryce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501453/
https://www.ncbi.nlm.nih.gov/pubmed/23185426
http://dx.doi.org/10.1371/journal.pone.0049751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501453/
https://www.ncbi.nlm.nih.gov/pubmed/23185426
http://dx.doi.org/10.1371/journal.pone.0049751

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