Cargando…

VLPs Displaying a Single L2 Epitope Induce Broadly Cross-Neutralizing Antibodies against Human Papillomavirus

BACKGROUND: Virus-like Particles (VLPs) display can be used to increase the immunogenicity of heterologous antigens. Here, we report the use of a bacteriophage MS2-based VLP display platform to develop a monovalent vaccine targeting a broadly neutralizing epitope in the minor capsid protein human pa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tumban, Ebenezer, Peabody, Julianne, Tyler, Mitchell, Peabody, David S., Chackerian, Bryce
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501453/ https://www.ncbi.nlm.nih.gov/pubmed/23185426 http://dx.doi.org/10.1371/journal.pone.0049751

Ejemplares similares

A Pan-HPV Vaccine Based on Bacteriophage PP7 VLPs Displaying Broadly Cross-Neutralizing Epitopes from the HPV Minor Capsid Protein, L2
por: Tumban, Ebenezer, et al.
Publicado: (2011)

Characterization of a spray-dried candidate HPV L2-VLP vaccine stored for multiple years at room temperature
por: Peabody, Julianne, et al.
Publicado: (2017)

Vaccination with VLPs Presenting a Linear Neutralizing Domain of S. aureus Hla Elicits Protective Immunity
por: Joyner, Jason A., et al.
Publicado: (2020)

Epitope-Specific Anti-hCG Vaccines on a Virus Like Particle Platform
por: Caldeira, Jerri, et al.
Publicado: (2015)

RNA Phage VLP-Based Vaccine Platforms
por: Peabody, David S., et al.
Publicado: (2021)

Factors That Govern the Induction of Long-Lived Antibody Responses
por: Chackerian, Bryce, et al.
Publicado: (2020)

Identification of an Immunogenic Mimic of a Conserved Epitope on the Plasmodium falciparum Blood Stage Antigen AMA1 Using Virus-Like Particle (VLP) Peptide Display
por: Crossey, Erin, et al.
Publicado: (2015)

Mixed Bacteriophage MS2-L2 VLPs Elicit Long-Lasting Protective Antibodies against HPV Pseudovirus 51
por: Yadav, Rashi, et al.
Publicado: (2021)

Engineering an Antibody V Gene-Selective Vaccine
por: Ronsard, Larance, et al.
Publicado: (2021)

Expansion and Refinement of Deep Sequence-Coupled Biopanning Technology for Epitope-Specific Antibody Responses in Human Serum
por: Warner, Nikole L., et al.
Publicado: (2020)

Pathogen-specific deep sequence-coupled biopanning: A method for surveying human antibody responses
por: Frietze, Kathryn M., et al.
Publicado: (2017)

Antibodies to Variable Domain 4 Linear Epitopes of the Chlamydia trachomatis Major Outer Membrane Protein Are Not Associated with Chlamydia Resolution or Reinfection in Women
por: Collar, Amanda L., et al.
Publicado: (2020)

The Immunogenicity of a VLP-based Malaria Vaccine Targeting CSP in Pregnant and Neonatal Mice
por: Jelínková, Lucie, et al.
Publicado: (2023)

A malaria vaccine candidate based on an epitope of the Plasmodium falciparum RH5 protein
por: Ord, Rosalynn L, et al.
Publicado: (2014)

A Current Update on Human Papillomavirus-Associated Head and Neck Cancers
por: Tumban, Ebenezer
Publicado: (2019)

A Viral Platform for Chemical Modification and Multivalent Display
por: Peabody, David S
Publicado: (2003)

Broadly neutralizing antibodies target a haemagglutinin anchor epitope
por: Guthmiller, Jenna J., et al.
Publicado: (2021)

Structure-Based Design of Porcine Circovirus Type 2 Chimeric VLPs (cVLPs) Displays Foreign Peptides on the Capsid Surface
por: Wang, Dongliang, et al.
Publicado: (2018)

Zika Virus-Derived E-DIII Protein Displayed on Immunologically Optimized VLPs Induces Neutralizing Antibodies without Causing Enhancement of Dengue Virus Infection
por: Cabral-Miranda, Gustavo, et al.
Publicado: (2019)

Computational Prediction of Broadly Neutralizing HIV-1 Antibody Epitopes from Neutralization Activity Data
por: Ferguson, Andrew L., et al.
Publicado: (2013)

A proof-of-concept study for the design of a VLP-based combinatorial HPV and placental malaria vaccine
por: Janitzek, Christoph M., et al.
Publicado: (2019)

Thermal Stability of RNA Phage Virus-Like Particles Displaying Foreign Peptides
por: Caldeira, Jerri C, et al.
Publicado: (2011)

Development of a Mimotope Vaccine Targeting the Staphylococcus aureus Quorum Sensing Pathway
por: O’Rourke, John P., et al.
Publicado: (2014)

Phage display as a tool for identifying HIV-1 broadly neutralizing antibodies
por: Chikaev, A.N., et al.
Publicado: (2021)

Qß Virus-like particle-based vaccine induces robust immunity and protects against tauopathy
por: Maphis, Nicole M., et al.
Publicado: (2019)

Immunogenicity of Plant-Produced Human Papillomavirus (HPV) Virus-Like Particles (VLPs)
por: Naupu, Paulina N., et al.
Publicado: (2020)

A Comparative Study on Delivery of Externally Attached DNA by Papillomavirus VLPs and Pseudoviruses
por: Brendle, Sarah, et al.
Publicado: (2021)

The Broad Neutralizing Antibody Responses after HIV-1 Superinfection Are Not Dominated by Antibodies Directed to Epitopes Common in Single Infection
por: Cortez, Valerie, et al.
Publicado: (2015)

Sensitivity of the ANUBIS and ATLAS Detectors to Neutral Long-Lived Particles Produced in $pp$ Collisions at the Large Hadron Collider
por: Satterthwaite, Thomas Peabody
Publicado: (2022)

Virus-like Particle-Based L2 Vaccines against HPVs: Where Are We Today?
por: Yadav, Rashi, et al.
Publicado: (2019)

Novel vomputational methods for predicting epitopes of potent and broadly neutralizing HIV-1 antibodies
por: Evans, MC, et al.
Publicado: (2012)

The importance of RSV F protein conformation in VLPs in stimulation of neutralizing antibody titers in mice previously infected with RSV
por: Cullen, Lori M., et al.
Publicado: (2017)

Epitope-Analyzer: A structure-based webtool to analyze broadly neutralizing epitopes
por: Montiel-Garcia, Daniel, et al.
Publicado: (2022)

Cross-Neutralization Potential of Native Human Papillomavirus N-Terminal L2 Epitopes
por: Conway, Michael J., et al.
Publicado: (2011)

Human papillomavirus 16L1-58L2 chimeric virus-like particles elicit durable neutralizing antibody responses against a broad-spectrum of human papillomavirus types
por: Chen, Xue, et al.
Publicado: (2017)

Identification of broadly neutralizing antibody epitopes in the HIV-1 envelope glycoprotein using evolutionary models
por: Lacerda, Miguel, et al.
Publicado: (2013)

Epitope resurfacing on dengue virus-like particle vaccine preparation to induce broad neutralizing antibody
por: Shen, Wen-Fan, et al.
Publicado: (2018)

Predicting HIV-1 broadly neutralizing antibody epitope networks using neutralization titers and a novel computational method
por: Evans, Mark C, et al.
Publicado: (2014)

Anti-V3 Monoclonal Antibodies Display Broad Neutralizing Activities against Multiple HIV-1 Subtypes
por: Hioe, Catarina E., et al.
Publicado: (2010)

Display of single-chain variable fragments on bacteriophage MS2 virus-like particles
por: Lino, Christopher A., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_1i9ut6m7j2fmeh9nqrj41h1ft9