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Orai1 Mediates Exacerbated Ca(2+) Entry in Dystrophic Skeletal Muscle

There is substantial evidence indicating that disruption of Ca(2+) homeostasis and activation of cytosolic proteases play a key role in the pathogenesis and progression of Duchenne Muscular Dystrophy (DMD). However, the exact nature of the Ca(2+) deregulation and the Ca(2+) signaling pathways that a...

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Detalles Bibliográficos
Autores principales: Zhao, Xiaoli, Moloughney, Joseph G., Zhang, Sai, Komazaki, Shinji, Weisleder, Noah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501460/
https://www.ncbi.nlm.nih.gov/pubmed/23185465
http://dx.doi.org/10.1371/journal.pone.0049862