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Orai1 Mediates Exacerbated Ca(2+) Entry in Dystrophic Skeletal Muscle
There is substantial evidence indicating that disruption of Ca(2+) homeostasis and activation of cytosolic proteases play a key role in the pathogenesis and progression of Duchenne Muscular Dystrophy (DMD). However, the exact nature of the Ca(2+) deregulation and the Ca(2+) signaling pathways that a...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501460/ https://www.ncbi.nlm.nih.gov/pubmed/23185465 http://dx.doi.org/10.1371/journal.pone.0049862 |