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Potential Downstream Target Genes of Aberrant ETS Transcription Factors Are Differentially Affected in Ewing’s Sarcoma and Prostate Carcinoma

FLI1 and ERG, the major ETS transcription factors involved in rearrangements in the Ewing’s sarcoma family of tumors (ESFT) and in prostate carcinomas (PCa), respectively, belong to the same subfamily, having 98% sequence identity in the DNA binding domain. We therefore decided to investigate whethe...

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Detalles Bibliográficos
Autores principales: Camões, Maria J., Paulo, Paula, Ribeiro, Franclim R., Barros-Silva, João D., Almeida, Mafalda, Costa, Vera L., Cerveira, Nuno, Skotheim, Rolf I., Lothe, Ragnhild A., Henrique, Rui, Jerónimo, Carmen, Teixeira, Manuel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501462/
https://www.ncbi.nlm.nih.gov/pubmed/23185447
http://dx.doi.org/10.1371/journal.pone.0049819