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Isoflurane Exposure during Mid-Adulthood Attenuates Age-Related Spatial Memory Impairment in APP/PS1 Transgenic Mice

Many in vitro findings suggest that isoflurane exposure might accelerate the process of Alzheimer Disease (AD); however, no behavioral evidence exists to support this theory. In the present study, we hypothesized that exposure of APP/PS1 transgenic mice to isoflurane during mid-adulthood, which is t...

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Detalles Bibliográficos
Autores principales: Su, Diansan, Zhao, Yanxing, Xu, Huan, Wang, Beilei, Chen, Xuemei, Chen, Jie, Wang, Xiangrui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501473/
https://www.ncbi.nlm.nih.gov/pubmed/23185565
http://dx.doi.org/10.1371/journal.pone.0050172