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Insights into the Structure, Correlated Motions, and Electrostatic Properties of Two HIV-1 gp120 V3 Loops

The V3 loop of the glycoprotein 120 (gp120) is a contact point for cell entry of HIV-1 leading to infection. Despite sequence variability and lack of specific structure, the highly flexible V3 loop possesses a well-defined role in recognizing and selecting cell-bound coreceptors CCR5 and CXCR4 throu...

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Detalles Bibliográficos
Autores principales: López de Victoria, Aliana, Tamamis, Phanourios, Kieslich, Chris A., Morikis, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501474/
https://www.ncbi.nlm.nih.gov/pubmed/23185486
http://dx.doi.org/10.1371/journal.pone.0049925