A Novel Bioassay for the Activity Determination of Therapeutic Human Brain Natriuretic Peptide (BNP)

BACKGROUND: Recombinant human brain natriuretic peptide (rhBNP) is an important peptide-based therapeutic drug indicated for the treatment of acute heart failure. Accurate determination of the potency of therapeutic rhBNP is crucial for the safety and efficacy of the drug. The current bioassay invol...

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Detalles Bibliográficos
Autores principales: Yu, Lei, Rao, Chunming, Shi, Xinchang, Li, Yonghong, Gao, Kai, Li, Xuguang, Wang, Junzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501489/
https://www.ncbi.nlm.nih.gov/pubmed/23185490
http://dx.doi.org/10.1371/journal.pone.0049934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501489/
https://www.ncbi.nlm.nih.gov/pubmed/23185490
http://dx.doi.org/10.1371/journal.pone.0049934

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