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Increasing Glucose 6-Phosphate Dehydrogenase Activity Restores Redox Balance in Vascular Endothelial Cells Exposed to High Glucose

Previous studies have shown that high glucose increases reactive oxygen species (ROS) in endothelial cells that contributes to vascular dysfunction and atherosclerosis. Accumulation of ROS is due to dysregulated redox balance between ROS-producing systems and antioxidant systems. Previous research f...

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Detalles Bibliográficos
Autores principales: Zhang, Zhaoyun, Yang, Zhihong, Zhu, Bo, Hu, Ji, Liew, Chong Wee, Zhang, Yingyi, Leopold, Jane A., Handy, Diane E., Loscalzo, Joseph, Stanton, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501497/
https://www.ncbi.nlm.nih.gov/pubmed/23185302
http://dx.doi.org/10.1371/journal.pone.0049128