Fibrin Clots Are Equilibrium Polymers That Can Be Remodeled Without Proteolytic Digestion

Fibrin polymerization is a necessary part of hemostasis but clots can obstruct blood vessels and cause heart attacks and strokes. The polymerization reactions are specific and controlled, involving strong knob-into-hole interactions to convert soluble fibrinogen into insoluble fibrin. It has long be...

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Detalles Bibliográficos
Autores principales: Chernysh, Irina N., Nagaswami, Chandrasekaran, Purohit, Prashant K., Weisel, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501649/
https://www.ncbi.nlm.nih.gov/pubmed/23170200
http://dx.doi.org/10.1038/srep00879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501649/
https://www.ncbi.nlm.nih.gov/pubmed/23170200
http://dx.doi.org/10.1038/srep00879

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