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Fibrin Clots Are Equilibrium Polymers That Can Be Remodeled Without Proteolytic Digestion
Fibrin polymerization is a necessary part of hemostasis but clots can obstruct blood vessels and cause heart attacks and strokes. The polymerization reactions are specific and controlled, involving strong knob-into-hole interactions to convert soluble fibrinogen into insoluble fibrin. It has long be...
Autores principales: | Chernysh, Irina N., Nagaswami, Chandrasekaran, Purohit, Prashant K., Weisel, John W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501649/ https://www.ncbi.nlm.nih.gov/pubmed/23170200 http://dx.doi.org/10.1038/srep00879 |
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