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Liver X Receptor Modulates Diabetic Retinopathy Outcome in a Mouse Model of Streptozotocin-Induced Diabetes

Endothelial progenitor cells (EPCs), critical for mediating vascular repair, are dysfunctional in a hyperglycemic and/or hypercholesterolemic environment. Their dysfunction contributes to the progression of diabetic macro- and microvascular complications. Activation of “cholesterol-sensing” nuclear...

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Detalles Bibliográficos
Autores principales: Hazra, Sugata, Rasheed, Adil, Bhatwadekar, Ashay, Wang, Xiaoxin, Shaw, Lynn C., Patel, Monika, Caballero, Sergio, Magomedova, Lilia, Solis, Nathaniel, Yan, Yuanqing, Wang, Weidong, Thinschmidt, Jeffrey S., Verma, Amrisha, Li, Qiuhong, Levi, Moshe, Cummins, Carolyn L., Grant, Maria B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501845/
https://www.ncbi.nlm.nih.gov/pubmed/22891211
http://dx.doi.org/10.2337/db11-1596