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Synthesis and antioxidant evaluation of some novel ortho-hydroxypyridine-4-one iron chelators

A series of ortho-hydroxypyridine-4-ones were prepared in high yields and evaluated for antioxidant and iron chelating activities. N(1)-H hydroxypyridinones Va, Vb, and Ve were the best radical scavengers in DPPH free radical scavenging assay. Compound Vb was proved to be the most potent compound in...

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Detalles Bibliográficos
Autores principales: Mohammadpour, M., Sadeghi, A., Fassihi, A., Saghaei, L., Movahedian, A., Rostami, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501926/
https://www.ncbi.nlm.nih.gov/pubmed/23181095