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Late morfofunctional alterations of the Sertoli cell caused by doxorubicin administered to prepubertal rats

BACKGROUND: Doxorubicin is a potent chemotherapeutic drug used against a variety of cancers. It acts through interaction with polymerases and topoisomerase II and free radical production. Doxorubicin activity is not specific to cancer cells and can also damage healthy cells, especially those undergo...

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Detalles Bibliográficos
Autores principales: Brilhante, Otávio, Okada, Fatima K, Sasso-Cerri, Estela, Stumpp, Taiza, Miraglia, Sandra M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502149/
https://www.ncbi.nlm.nih.gov/pubmed/22967030
http://dx.doi.org/10.1186/1477-7827-10-79